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In sexual stimulation, blood vessels in the penis relax. The corpora cavernosa fill with blood and pressure builds, the penis reaches stiffness. The active ingredient in (Sildenafil or sildenafil citrate) facilitates the expansion of blood vessels in the penis, and so blood can flow when a man is sexually excited, allowing erections.
or Viagra (Sildenafil) is a potent and selective inhibitor of specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. molecular structure is similar to that of cGMP and acts as a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and better erections.
It is used to treat erectile dysfunction.
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